Long-Term Comparison of Fixed- and Mobile-Bearing Total Knee Arthroplasties (TKAs) in Patients With OA ≤50 Years Old

Long-Term Comparison of Fixed- and Mobile-Bearing Total Knee Arthroplasties in Patients With Osteoarthritis Younger Than Fifty Years of Age

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01361152

Enrollment

216

Registered

2011-05-26

Start date

1993-04-30

Completion date

2011-03-31

Last updated

2011-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Keywords

total knee arthroplasty, fixed-bearing, mobile-bearing, long-term

Brief summary

The purpose of the prospective study was to evaluate the minimum fifteen year follow-up of prospective total knee arthroplasties performed in patients younger than fifty years of age with osteoarthritis, using fixed- and mobile-bearing knee prostheses in the same patients, to compare 1. functional scores 2. rates of radiographic failure 3. revision rates 4. survivorship

Detailed description

The randomized prospective comparison of fixed- and mobile-bearing total knee designs in the same patients younger than fifty years of age is limited. The purpose of this study was to compare the long-term clinical and radiographic results of fixed- and mobile-bearing total knee arthroplasties in patients younger than fifty years of age with osteoarthritis.

Interventions

DEVICEanatomic modular fixed-bearing

anatomic modular (AMK; DePuy) fixed-bearing prosthesis

DEVICElow contact stress rotating platform mobile-bearing

low contact stress rotating platform (LCS RP; DePuy) mobile-bearing prosthesis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

29 Years to 50 Years

Healthy volunteers

Inclusion criteria

* End-stage osteoarthritis of the knee joint requiring total knee arthroplasty with bilateral disease

Exclusion criteria

* Inflammatory disease * Patient with other Lower extremity disease which may affect functional outcome * Neurologic disease effecting patients lower extremity * Revision surgery * Patient not medically cleared for bilateral surgery

Design outcomes

Primary

Measure	Time frame	Description
Improvement in Knee Society Knee Score	18 years	change in knee score will be compared with initial score, until follow up of 18 years

Secondary

Measure	Time frame	Description
Improvement in the range of motion	18 years	change in the range of motion of knee joint will be compared with the initial value, until follow up of 18 years.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026