MI Mortality Risk and Between-hospital Risk Variation in the United Kingdom and Sweden

Compare the Patient Risk and Between-hospital Variation in Myocardial Infarction Mortality in the United Kingdom and Sweden

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01359033

Enrollment

510863

Registered

2011-05-24

Start date

2011-03-31

Completion date

2014-12-31

Last updated

2017-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Keywords

Myocardial Infarction, UK, Sweden, National audit registry, MINAP, RIKS-HIA

Brief summary

The study aims to investigate the differences in survival trajectories and hospital variability in myocardial infarction (MI) mortality rates in the UK and Sweden.

Detailed description

Limited evidence is available in comparing hospital level care and reference mortality risks between countries, due to the scarce availability of nationwide coronary heart disease data. The demographics and medical expenditure percentage are comparable in the United Kingdom and Sweden; however, the in-hospital case-fatality rates within 30 days after admission for acute myocardial infarction was greater in the UK than Sweden (6.3% versus 2.9%)(OECD, 2009). To investigate the discrepancy, the current study aims to compare the mortality risk differences and associated explanatory factors between the two countries. Results of the study can contribute to myocardial infarction care implementation in the UK and Sweden. The UK Myocardial Ischaemia National Audit Project (MINAP)and Register of Information and Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA) are few quality national registries currently available for acute coronary syndrome. Using data from the MINAP and RIKS-HIA, we propose to investigate (1)the survival trajectories for a reference patient with myocardial infarction and (2) hospital variability in myocardial infarction mortality rate in the UK and Sweden, adjusted for important patient-level and hospital-level covariates.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged above 30 years old who had hospital admission for acute myocardial infarction. * Admission period ranged from 1st January, 2004 to 31th December, 2008.

Exclusion criteria

* Patients with missing data in the admission time and/or primary outcomes.

Design outcomes

Primary

Measure	Time frame	Description
30-day mortality	30-day	all-cause mortality at 30-day following hospitalization for acute Myocardial Infarction

Secondary

Measure	Time frame	Description
1-year mortality	1 year	all-cause mortality at 1-year following hospitalization for acute Myocardial Infarction

Countries

Sweden, United Kingdom

Outcome results