Motor Activity
Conditions
Brief summary
Today, there is an important lack of knowledge on child metabolism and the effects of phytochemical-rich foods, which includes fruits and vegetables and plant-derived foods. Here, the investigators will monitor the metabolism of children using minimally invasive techniques at rest, and with physical/mental activities and assess the changes associated with the intake of cocoa-based food.
Interventions
OTHERcocoa-based food
single intake of cocoa-based food
Sponsors
Société des Produits Nestlé (SPN)
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
8 Years to 13 Years
Healthy volunteers
Yes
Inclusion criteria
All subjects must comply with all the following inclusion criteria: * Healthy and physically active, and no diabetes or metabolism related disorders in their first degree relatives (as determined by medical and activity questionnaire) * Caucasian, with English as a first language and an adequate standard of literacy. * BMI adjusted for age and gender which falls between the 9th and 91st as shown in the Child Growth Foundation BMI growth charts * 8-13 years of age * Having obtained his/her informed assent * Having obtained his/her legal representative's informed consent * Willing to allow their family doctor (GP) to be informed about their participation in this study
Exclusion criteria
Subjects representing one or more of the following criteria are excluded from participation in the study. * Post-pubertal * Taking any medication * Smoker * Undergoing medical treatment or investigations * Body mass index \> 24 * Suffer from chronic diseases (with regular intake of drugs, medical history) * Vegetarians * Vaccination in the last 4 months * Any know food allergies or intolerance * Pregnancy * Special diet or weight loss program (e.g. Atkins diet) * Acute illness * Fever, cold, flu * Participation in a cholesterol management program with functional foods like food supplement enriched in omega-3 fatty acids, dairy products enriched with phytosterols (margarines, yoghurts).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood glucose concentration | Baseline will be fasting, and monitoring measures up to 7 hours after consumption | Time Frame: the effects of one-off consumption will be measured over a 7-8 hours period. Baseline will be fasting, and monitoring measures up to 7 hours after consumption. The subjects will be on controlled diet the day prior to the visit. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Metabolic monitoring | measured over a 7-8 hours period | Time Frame: the effects of one-off consumption will be measured over a 7-8 hours period. Baseline will be fasting, and monitoring measures up to 7 hours after consumption. The subjects will be on controlled diet the day prior to the visit. |
| physical monitoring | two hours and four hours after concumption | Time Frame: the effects of one-off consumption will be measured two hours and four hours after consumption with 45 min physical activity sessions. |
| mental monitoring | 3.3 hours after intake | Time Frame: the effects of one-off consumption will be measured around 3.3 hours after intake. Baseline will be at fasting before intake. |
Countries
United Kingdom
Outcome results
None listed