Poor Semen Quality
Conditions
Keywords
Semen quality, Plant extracts
Brief summary
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.
Interventions
DIETARY_SUPPLEMENTExtracts of Punica granatum and Alpinia galanga
Tablets, two in the morning and two in the evening
DIETARY_SUPPLEMENTPlacebo
Tablets, two in the morning and two in the evening
Sponsors
Videns- og Forskningscenter for Alternativ Behandling
Horsens Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Reduced semen quality
Exclusion criteria
* Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Count of motile sperm per ejaculate | Each participant is given plant extract for three months with flanking semen analyses. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Morphology: percentage of morphologically abnormal sperm in the ejaculate | Each participant is given plant extract for three months with flanking semen analyses. | If we find an increase in the primary outcome measure in data from participants receiving plant extracts and not in those receiving placebo tablets, we wish to further investigate whether sperm morphology also improves when consuming the plant extracts, e.g. whether the percentage of abnormal sperm in an ejaculate decreases in the group of participants receiving the active plant extracts |
Countries
Denmark
Outcome results
None listed