Effect of Hemodialysis Membranes on Platelet Count

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01356576

Enrollment

Registered

2011-05-19

Start date

2010-09-30

Completion date

2011-09-30

Last updated

2014-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombocytopenia

Brief summary

The purpose of this study is to determine if there is a drop in platelet count after hemodialysis. Hemodialysis membranes are known to activate complement and cause a drop in platelets and sometimes in white blood cells. The investigators are going to study one of the membranes which is the Fresenius Optiflux® to check if it causes a drop in platelets.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patients on Hemodialysis for \>=6 months

Exclusion criteria

* Hematological Cancers * Myelodysplastic syndromes * Baseline thrombocytopenia * Acute infections (patients on antibiotics) * Patients with Immune thrombocytopenic purpura (ITP)/Thrombotic thrombocytopenic purpura (TTP) * HIV * Liver disease

Design outcomes

Primary

Measure	Time frame
Drop in platelet counts	90 minutes through hemodialysis and immediately after finishing hemodialysis

Countries

United States

Outcome results