Costimulatory Molecules as Biomarkers in Cystic Fibrosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01353950

Enrollment

Registered

2011-05-16

Start date

2011-07-31

Completion date

2013-06-30

Last updated

2017-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis

Keywords

Costimulatory molecules, Cystic Fibrosis, Biomarkers

Brief summary

The purpose of this study is to investigate the expression of a certain class of molecules, called costimulatory molecules, in humans with Cystic Fibrosis. Cystic Fibrosis is a genetic disorder which renders the lung susceptible to persistent inflammation which, at times, can worsen, resulting in accelerated decline in lung function and eventually death or transplant. Our goal is to determine if the levels of costimulatory markers can be used to predict exacerbation and subsequent lung function decline in subjects with Cystic Fibrosis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Willingness to participate

Exclusion criteria

* Presence of HIV * Presence of Lymphoma/Leukemia * Presence of Lung or other solid organ Transplant * Pregnancy

Countries

United States

Outcome results