Acne Inversa, Hidradenitis, Hidradenitis Suppurativa, Wounds
Conditions
Keywords
Non healing ulcer, Wound, Hidradenitis suppurativa, Acne Inversa, Hidradenitis
Brief summary
The purpose of the WE-HEAL Study is to help researchers use human tissue samples and health records to study the reasons why some patients heal quickly and some have problems healing wounds. All patients seen with an open wound or hidradenitis suppurativa are invited to participate. Information from this research may help to understand how to prevent and treat certain diseases.
Interventions
None listed
Sponsors
National Center for Research Resources (NCRR)
National Institute of Nursing Research (NINR)
George Washington University
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
1. Age \>18 2. Open wound or hidradenitis suppurativa 3. English speaking 4. Able to give informed consent
Exclusion criteria
1. Non-English speaking. 2. Unable to give informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to wound healing | 10 years | This prospective study will establish a biobank for collection of residual biopsy tissue discarded after debridement, and collection of other biospecimens at the discretion of the investigators including wound fluid and serum samples. Patients will also permit linking of biosamples to clinical outcomes data. Using a primary outcome of wound healing we will compare biomarkers on tissue, serum and wound fluid from patients with non-healing ulcers and hidradenitis to identify angiogenic and vasculogenic pathways that are dysregulated in patients with wound healing problems. |
Countries
United States
Outcome results
None listed