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Using Computers to Assist in the Diagnosis and Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Using Computers to Assist in the Diagnosis and Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01351064
Enrollment
84
Registered
2011-05-10
Start date
2010-07-31
Completion date
2012-07-31
Last updated
2016-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Hyperactivity Disorder

Keywords

ADHD

Brief summary

Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in children. Prevalence rates in the United States range from 2% to 18% depending on diagnostic criteria and population studied. Primary care physicians, especially pediatricians, have historically played a large role in the diagnosis and treatment of ADHD. Despite the existence of authoritative guidelines to assist primary care physicians, ample evidence demonstrates that they continue to diagnose and treat this disorder suboptimally. This is due, in part, to a lack of training and cumbersome delivery system designs. Modern computer decision support strategies offer the best hope of equipping general practitioners to deal with the mental health epidemic of ADHD. The investigators have developed a novel decision support system for implementing clinical guidelines in pediatric practice. CHICA (Child Health Improvement through Computer Automation) combines three elements: (1) pediatric guidelines encoded in Arden Syntax; (2) a dynamic, scannable paper user interface; and (3) an HL7-compliant interface to existing electronic medical record systems. The result is a system that both delivers just-in-time patient-relevant guidelines to physicians during the clinical encounter, and accurately captures structured data from all who interact with it. Preliminary work with CHICA has demonstrated the feasibility of using the system to implement and evaluate clinical guidelines. The investigators propose to expand CHICA to include ADHD diagnosis and treatment guidelines. The investigators hypothesize that implementation of the ADHD guidelines will result in better outcomes, including higher rates of adherence to recommendations and improved patient functioning.

Detailed description

Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in children. Prevalence rates in the United States range from 2% to 18% depending on diagnostic criteria and population studied. Primary care physicians, especially pediatricians, have historically played a large role in the diagnosis and treatment of ADHD. Despite the existence of authoritative guidelines to assist primary care physicians, ample evidence demonstrates that they continue to diagnose and treat this disorder suboptimally. This is due, in part, to a lack of training and cumbersome delivery system designs. Modern computer decision support strategies offer the best hope of equipping general practitioners to deal with the mental health epidemic of ADHD. The investigators have developed a novel decision support system for implementing clinical guidelines in pediatric practice. CHICA (Child Health Improvement through Computer Automation) combines three elements: (1) pediatric guidelines encoded in Arden Syntax; (2) a dynamic, scannable paper user interface; and (3) an HL7-compliant interface to existing electronic medical record systems. The result is a system that both delivers just-in-time patient-relevant guidelines to physicians during the clinical encounter, and accurately captures structured data from all who interact with it. Preliminary work with CHICA has demonstrated the feasibility of using the system to implement and evaluate clinical guidelines. The investigators propose to expand CHICA to include ADHD diagnosis and treatment guidelines. The investigators hypothesize that implementation of the ADHD guidelines will result in better outcomes, including higher rates of adherence to recommendations and improved patient functioning. The specific research aims of this proposal are: Aim 1: Expand and modify an existing computer-based decision support system (CHICA) to include ADHD treatment and diagnosis guideline rules as well as the capability to fax data directly into the medical record. Aim 2: Evaluate the effect of the CHICA system on the processes of ADHD care in pediatric practices, including adherence to guidelines for ADHD treatment and diagnosis.

Interventions

OTHERCHICA ADHD Module

This module was added to CHICA to help diagnose and manage ADHD

Sponsors

National Library of Medicine (NLM)
CollaboratorNIH
Indiana University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
5 Years to 12 Years
Healthy volunteers
Yes

Inclusion criteria

* Child between age 5 and 12 years seen in one of our clinics

Exclusion criteria

* Child outside the age range or who is not seen in one of our clinics.

Design outcomes

Primary

MeasureTime frame
Number of Children Diagnosed With ADHD With Structured Diagnostic Assessmentone year

Secondary

MeasureTime frame
Percent of Patients Receiving ADHD Care Componentone year

Countries

United States

Participant flow

Participants by arm

ArmCount
CHICA ADHD Module
This arm received The CHICA ADHD Module CHICA ADHD Module: This module was added to CHICA to help diagnose and manage ADHD
42
CHICA ADHD Control
This arm received CHICA without the ADHD module
42
Total84

Baseline characteristics

CharacteristicCHICA ADHD ModuleCHICA ADHD ControlTotal
Age, Categorical
<=18 years
42 Participants42 Participants84 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
0 Participants0 Participants0 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Black or African American
19 Participants29 Participants48 Participants
Race (NIH/OMB)
More than one race
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
2 Participants4 Participants6 Participants
Race (NIH/OMB)
White
21 Participants9 Participants30 Participants
Sex: Female, Male
Female
13 Participants11 Participants24 Participants
Sex: Female, Male
Male
29 Participants31 Participants60 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
— / —— / —
other
Total, other adverse events
0 / 420 / 42
serious
Total, serious adverse events
0 / 420 / 42

Outcome results

Primary

Number of Children Diagnosed With ADHD With Structured Diagnostic Assessment

Time frame: one year

ArmMeasureValue (NUMBER)
CHICA ADHD ModuleNumber of Children Diagnosed With ADHD With Structured Diagnostic Assessment34 number of kids
CHICA ADHD ControlNumber of Children Diagnosed With ADHD With Structured Diagnostic Assessment16 number of kids
Secondary

Percent of Patients Receiving ADHD Care Component

Time frame: one year

ArmMeasureGroupValue (NUMBER)
CHICA ADHD ModulePercent of Patients Receiving ADHD Care ComponentMedication adjusted45 percentage of participants
CHICA ADHD ModulePercent of Patients Receiving ADHD Care ComponentReassessment of symptoms50 percentage of participants
CHICA ADHD ModulePercent of Patients Receiving ADHD Care ComponentMental Health Referral74 percentage of participants
CHICA ADHD ModulePercent of Patients Receiving ADHD Care ComponentMental Health Visit67 percentage of participants
CHICA ADHD ControlPercent of Patients Receiving ADHD Care ComponentMental Health Visit48 percentage of participants
CHICA ADHD ControlPercent of Patients Receiving ADHD Care ComponentMedication adjusted33 percentage of participants
CHICA ADHD ControlPercent of Patients Receiving ADHD Care ComponentMental Health Referral55 percentage of participants
CHICA ADHD ControlPercent of Patients Receiving ADHD Care ComponentReassessment of symptoms33 percentage of participants

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026