Health-related Quality of Life of Patients With Esophageal Cancer After Surgery

Health-related Quality of Life of Patients With Esophageal Cancer After Surgery in China: A Prospective Cohort Study From Multi-center

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01349517

Enrollment

400

Registered

2011-05-06

Start date

2011-05-31

Completion date

2016-12-31

Last updated

2011-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer

Keywords

health-related quality of life(HRQL), Esophageal Cancer

Brief summary

The purpose of this multi-center prospective cohort study is to study the health-related quality of life (HRQL) together with other outcomes of patients with esophageal cancer after surgery in China.

Detailed description

* To study the influence of health-related quality of life of patients with esophageal cancer before and after surgery. * To compare the impact of different procedures on the the health-related quality of life of patients with esophageal cancer. * To compare morbidities and oncological results(3,5- year survival) from different procedures.

Interventions

PROCEDUREMIE

The patients in this group would perform minimal invasive three-incision subtotal esophagectomy (thoracoscopic and/or laparoscopic)

PROCEDUREThree-incision thoracotomy

The patients in this group would perform three-incision subtotal esophagectomy (thoracotomy and laparotomy)

PROCEDUREIvor-Lewis esophagectomy

The patients in this group would underwent Ivor-Lewis esophagectomy

PROCEDURESweet esophagectomy

The patients in this group would underwent Sweet esophagectomy.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Clinical stage I/II esophageal cancer * Normal blood test of basic metabolism panel * Pulmonary function: FEV1 \> 1.2L, FEV1% \> 50%, DLCO \> 50% * Heart function: NY grade I and grade II

Exclusion criteria

* Mental disorders * Combination with other cancers * With a previous history of thoracic or ventral surgery

Design outcomes

Primary

Measure	Time frame	Description
Health related quality of life	postoperative 2 year	Health related quality of life from the different precedure groups (assessed by EORTC QLQ C-30 and OES-18)

Secondary

Measure	Time frame	Description
Morbidity Mortality Survival rate	5 years	* Perioperative morbidity and mortality from the different precedure groups. * 3-and 5-year survival rate between the groups.

Countries

China

Contacts

Primary ContactTan Lijie, MD

tan.lijie@zs-hospital.sh.cn86-021-64041990

Backup ContactWang Hao, MM

wang.hao@zs-hospital.sh.cn86-021-64041990

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026