Conjunctivitis, Viral, Adenoviridae Infections
Conditions
Keywords
Conjunctivitis, Viral, Adenoviridae Infections, Ganciclovir, Adenovirus Keratoconjunctivitis, Treatment of viral conjunctivitis
Brief summary
Ganciclovir ophthalmic gel delivers multiple advantages in the treatment and prophylaxis of herpetic keratitis and shows potential for effectiveness against other viral ocular infections. The majority of adenoviral conjunctivitis will resolve without damaging vision, however, the investigators have no way to determine which cases will progress to ocular complications such as corneal infiltrates and pseudomembranes. Our purpose is to evaluate the efficacy of the Ganciclovir gel 0.15% in preventing ocular complications after adenoviral conjunctivitis.
Interventions
DRUGGanciclovir
Ganciclovir 0.15% Ophthalmic gel
DRUGArtificial tear
Artificial tear 5 times per day
Sponsors
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* onset of symptoms for five days or less * eighteen years old or more * not pregnant or breastfeeding * be able to understand and sign the consent term
Exclusion criteria
* use of antibiotic or corticoid 30 days before * monocular vision * keratopathy or other ocular diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement of symptoms of conjunctivitis (pain relief) | 6 days |
Countries
Brazil
Outcome results
None listed