Aggressive Prostate Cancers in Elderly Patients

Patients Aged More Than 70 Had More Aggressive Prostate Cancers and Higher Risk of Biochemical Recurrence in Korea

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01347476

Enrollment

1333

Registered

2011-05-04

Start date

2010-01-31

Completion date

2010-10-31

Last updated

2011-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostatic Neoplasms

Keywords

prostate-specific antigen, radical prostatectomy

Brief summary

Patients aged 70 years or older had a higher possibility of high risk cancer than younger patients.

Detailed description

Patients aged 70 years or older had a higher risk of advanced prostate cancer and shorter BCR-free survival than younger ones. Definite treatment of clinically localized prostate cancer should be actively considered in well-selected healthy patients older than 70 years.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

40 Years to 80 Years

Healthy volunteers

Inclusion criteria

* clinically localized prostate cancer * good health status * follow-up period more than 12 months

Exclusion criteria

* insufficient clinical data * poor health status * clinically advanced prostate cancer

Design outcomes

Primary

Measure	Time frame	Description
biochemical recurrences (BCR)	5 year-BCR	BCR was defined as two consecutive increasing PSA values of more than 0.2 ng/mL

Secondary

Measure	Time frame	Description
pathologic outcomes	postoperative 1 week	biopsy or pathologic Gleason scores, mean percent of positive cores and tumor volume percent, Extracapsular extension and seminal vesicle invasion

Countries

South Korea

Outcome results