Multi-center Observational Study to Evaluate Epidemiology and Resistance Patterns of Common ICU-Infections (MOSER)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01346735

Acronym

MOSER

Enrollment

381

Registered

2011-05-03

Start date

2011-08-31

Completion date

2012-10-31

Last updated

2016-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nosocomial Infections

Keywords

Ventilator associated pneumonia, Catheter related blood stream infection, Catheter associated urinary tract infection, ICU-related infections (VAP, CAUTI and CRBSI), India

Brief summary

Most literature on ICU infections and the resistant patterns comes from the western literature. This data may not truly reflect the incidence, epidemiology and resistance patterns in developing countries such as India. However, empiric antibiotic therapy is generally initiated using western guidelines. This can potentially lead to inadequate, inappropriate and ineffective empiric antibiotic therapy for ICU infections in the Indian setting. Hence in this multi-center observational study, we seek to: 1. To determine the incidence of ICU-related infections (VAP, CAUTI and CRBSI) in India 2. To explore the microbiology, resistance and treatment patterns of these infections

Interventions

OTHERNo intervention

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. ICU stay \>48 hours 2. One of the following infections (VAP, CAUTI or CRBSI)

Exclusion criteria

1. Index ICU stay \< 48 hours 2. Re-admissions to the ICU within the same hospitalization 3. Age \>18 years or \<70 years 4. Known HIV serology positivity 5. Burns 6. Solid organ or Bone-marrow transplant 7. No ICU-acquired infections (specifically VAP, CAUTI and CRBSI)

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026