Time - Related Cuff Pressure and Volume of the Laryngeal Tube With the Use of Nitrous Oxide

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01346384

Enrollment

Registered

2011-05-03

Start date

2008-05-31

Completion date

2009-12-31

Last updated

2011-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult Disease

Keywords

intracuff pressure, laryngeal tube, nitrous oxide

Brief summary

The purpose of this study is to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O.

Detailed description

Background : The laryngeal tube airway (LT) is an extraglottic airway device with a proximal and distal conical cuff designed to secure a patient's airway during either spontaneous breathing or controlled ventilation. Application of this device with the use of N2O may be related to the ischemic change of the oropharyngeal mucosa. The objective of this study was to investigate the time-related intracuff pressure and volume change (which reflects the pharyngeal pressure) of the LT during anesthesia with N2O. Methods : Seventy-five patients were studied with the use of LT size 4. N2O (66%) and isoflurane were used to maintain anesthesia. Initial intracuff pressure and volume were recorded for airway sealing during ventilation. Time-course changes of the intracuff pressure followed by recording every 10 min. If the intracuff pressure reached 100 cmH2O, the cuff was deflated to the initial intracuff pressure and the volume of deflated air and postoperative airway complications were recorded.

Interventions

DEVICElaryngeal tube (VBM Medizintechnik)

laryngeal tube number 4

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

15 Years to 75 Years

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologist physical status I or II * Undergoing elective orthopedic surgery and surgery of breast under general anesthesia with an expected duration of 60 min or more

Exclusion criteria

* Height was \< 155 or \>180 cm (for the use of laryngeal tube size 4) * Body mass index ≥35 kg/m2 * Preexisting laryngotracheal disease * Risk of pulmonary aspiration of gastric contents.

Design outcomes

Primary

Measure	Time frame	Description
intracuff pressure	1-4 hours	measured intracuff pressure of LT with N2O during intraoperative period

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026