Coronary Heart Disease
Conditions
Brief summary
The aim of the study is to investigate if cow feeding regimes affects concentration of plasma phytanic acid and risk markers of the metabolic syndrome in human.
Interventions
DIETARY_SUPPLEMENTmilk fat
45 g milk fat per day in 4 weeks
Sponsors
The Danish Dairy Research Foundation, Denmark
The Danish Council for Strategic Research
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* sign written consent * Age: 20-42 * BMI: 20-30 * increased risk of developing MS * refrain from dietary supplements and blood donations prior to, and during the study
Exclusion criteria
* poor compliance * if they suffering from any chronic or long lasting illness * abuse of alcohol or medicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma phytanic acid | before and after the intervention (4 weeks) |
Secondary
| Measure | Time frame |
|---|---|
| LDL cholesterol | before and after the intervention (4 weeks) |
| HDL cholesterol | before and after the intervention (4 weeks) |
| triacylglycerol | before and after the intervention (4 weeks) |
| total cholesterol | before and after the intervention (4 weeks) |
| insulin | before and after the intervention (4 weeks) |
| glucose | before and after the intervention (4 weeks) |
| fatty acid composition in plasma | before and after the intervention (4 weeks) |
| C-reactive protein | before and after the intervention (4 weeks) |
Countries
Denmark
Outcome results
None listed