High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis

High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Knee and Hip Endoprosthesis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01335815

Enrollment

200

Registered

2011-04-14

Start date

2011-03-31

Completion date

2013-03-31

Last updated

2011-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative Myocardial Infarctions, Pulmonary Embolism

Brief summary

Summary: The purpose of the study is to prove if the biomarker high sensitive troponin T (hsTnT) and the biomarker of endogenous stress copeptin can serve as surrogate parameter of prognosis in patients with elective knee and hip total endoprosthesis.

Detailed description

Consecutively, high sensitive troponin T and copeptin will be measured in all patients with elective knee and hip endoprosthesis in the orthopedic department of the University of Heidelberg. The blood is taken during the routine blood testes if possible, on admission and the days 1-4 following the operation. Usual baseline characteristics are taken as well as usual blood results (hb, cholesterol and so on). Primary endpoint is the detection of perioperative myocardial infarction and pulmonary embolism.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Consecutive patients with elective knee and hip endoprosthesis

Exclusion criteria

* Not willing or not able to take part in the observational trial * No written inform consent

Design outcomes

Primary

Measure	Time frame
Prevalence of perioperative myocardial infarction and pulmonary embolism	Until 96h after operation

Countries

Germany

Contacts

Primary Contactevangelos Giannitsis, Prof. Dr.

Evangelos_Giannitsis@med.uni-heidelberg.de0049-6221-56-38686

Outcome results