Mechanism of Action of Vichy Catalan Water

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01334840

Enrollment

Registered

2011-04-13

Start date

2009-11-30

Completion date

2010-07-31

Last updated

2014-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases

Keywords

Cardiovascular risk, Cholecystokinin, Gallbladder emptying, Lipid absorption, Postprandial triacylglycerols, Sodium-bicarbonated mineral water

Brief summary

Water consumption is essential to maintain hydration and good health. Sodium-bicarbonated mineral waters are reported to have beneficial digestive and hypocholesterolemic properties. The aim of this study was to investigate the effects of the consumption of a sodium-bicarbonated mineral water (BW) with or without a meal, compared to a low mineral content water as a control water (CW), on postprandial serum triacylglycerols (TAG), cholecystokinin (CCK), and gallbladder volume.

Interventions

DIETARY_SUPPLEMENTBicarbonated mineral water

Volunteers fasted overnight consumed: 0.5 L of the bicarbonated mineral water without meal or, 0.5 L of the bicarbonated mineral water with meal

DIETARY_SUPPLEMENTMineral water low in mineral content (control)

Volunteers fasted overnight consumed: 0.5 L of the control water without meal or, 0.5 L of the control water with meal

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult (\>18 and \<40 years) * BMI \>18 and \<30 kg/m2

Exclusion criteria

* Age \<18 and \> 40 years * TAG \> 250 mg/dL (2.82 mmol/L) * Being a usual consumer of carbonic mineral water * Obesity * Diabetes * Hypertension or digestive, liver and renal disease * Biliary obstruction * Eating disorders * Being under medication that could affect lipid metabolism * Consumption of functional foods that could affect lipid metabolism (food containing n-3 fatty acids or phytosterols)

Design outcomes

Primary

Measure	Time frame
Serum triacylglycerols	Baseline

Secondary

Measure	Time frame
Serum glucose	Baseline
Serum insulin	Baseline
Cholecystokinin	Baseline
Gallbladder volume	Baseline
Aldosterone	Baseline

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 13, 2026