Tinnitus and Arterial Hypertension

Tinnitus and Arterial Hypertension.is There Any Relationship?

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01333683

Enrollment

100

Registered

2011-04-12

Start date

2011-04-30

Completion date

2015-10-31

Last updated

2015-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arterial Hypertension, Hearing Loss, Tinnitus

Keywords

tinnitus, hearing loss, arterial hypertension, ototoxicity

Brief summary

Many authors link tinnitus to arterial hypertension. The aim of this study is to establish a possible relationship between them, analyze the severity of tinnitus related to arterial hypertension and analyze a possible influence of ototoxic drugs used to treat arterial hypertension

Detailed description

Arterial hypertension has been cited as a possible tinnitus etiology. Vascular abnormalities associated with it may account for cochlear and central nervous system. However, a relationship between tinnitus and arterial hypertension has never been established. The aim of this study is to analyze this relationship, comparing groups with and without arterial hypertension and the incidence of tinnitus amongst them. Inclusion and exclusion criteria try to isolate arterial hypertension as the main etiological factor, as much as possible. Presbycusis, noise exposure, metabolical diseases and genetic factors will be ruled out. A comparison will be performed inside the arterial hypertension group between subgroups that use or not ototoxic medications, such as furosemide and beta-blockers

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 49 Years

Healthy volunteers

Yes

Inclusion criteria

* age between 40 and 50 * arterial hypertension for group 1 * at least 5 years standing arterial hypertension

Exclusion criteria

* chronic noise exposure * metabolic diseases * family antecedents of hearing loss (except for presbycusis) * pregnant women * use of ototoxic drugs (except for anti-hypertensives)

Design outcomes

Primary

Measure	Time frame	Description
Incidence of tinnitus - have tinnitus x don't have tinnitus	Up to 6 months	The purpose of this study is to compare tinnitus incidence between patients with and without arterial hypertension.

Secondary

Measure	Time frame	Description
Severity of tinnitus - Tinnitus Handicap Inventory	Up to 6 months	Severity of tinnitus measured by Tinnitus Handicap Inventory, to evaluate differences between patients with and without arterial hypertension

Countries

Brazil

Outcome results