GLP-1: Acute Effects on Kidney Function in Healthy Men

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01333163

Enrollment

Registered

2011-04-11

Start date

2011-05-31

Completion date

2011-12-31

Last updated

2011-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Functional

Brief summary

The purpose of this study is to investigate how Glucagon-Like Peptide 1 (GLP-1) affects kidney function in healthy young men. The hypothesis is that GLP-1 induces a positive effect on kidney hemodynamics.

Interventions

BIOLOGICALHuman GLP-1 (7-36) amide

2 hour IV infusion, 1,5pmol/min/kg.

BIOLOGICALIsotone NaCl

2 hours IV infusion.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

MALE

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy young men

Exclusion criteria

* Any chronic diseases

Design outcomes

Primary

Measure	Time frame
Glomerular Filtration Rate	Every 20 minutes for 6 hours

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026