Cardiac Disorder
Conditions
Keywords
cardiopulmonary bypass, mesenteric, microcirculatory function
Brief summary
The purpose of this study is to determine whether cardiopulmonary bypass affects mesenteric microcirculatory function, using sublingual evaluation, in cardiac surgery.
Interventions
OTHERsublingual microcirculatory evaluation
TNF, ICAM, syndecan-1, heparan sulfate
Sponsors
University Hospital, Rouen
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* age\> 18 years old * aortic valvular disease needing aortic valve replacement
Exclusion criteria
* Age\<18 years old * emergent cardiac surgery * other cardiac surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Microcirculatory impairment | 36 months | Mean flow index measurement and capillar density study |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORFabien Doguet, MD
University Hospital, Rouen
Outcome results
None listed