Chronic Periodontitis
Conditions
Keywords
Photodynamic therapy, Light-emitting diode, toluidine blue, scaling and root planing
Brief summary
The aim of this randomized clinical trial is to clinically evaluate the effectiveness of the adjunctive use of photodynamic therapy (PDT) with an light-emitting diode (LED) light source in the treatment of chronic periodontitis.
Interventions
using Light-emitting diod(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark) in the presence of toluidine blue O (TBO)
OTHERLight-emitting diod Irradiation
625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark
OTHERapplying Photosensitizer
toluidine blue O is applied at the bottom of each periodontal pocket
Sponsors
Tehran University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. clinically diagnosis of advanced chronic periodontitis with more than 3 mm clinical attachment loss 2. presence of at least two teeth with probing depth of 4 to 6 mm without furcation involvement in each quadrant 3. at least 16 remaining teeth 4. no periodontal treatment in the past 12 months 5. no evidence of systemic disease related to periodontal problems 6. no use of antibiotics for the past 6 months 7. No smoking more than 10 cigarettes per day 8. no addiction to any kind of drugs 9. no pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing pocket depth | Baseline, one month, three month | distance from gingival margin to base of the clinical pocket by William's periodontal probe |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinical attachment loss | Baseline, one month, three month | distance in millimeter from a fix reference point (cement-enamel junction) to the bottom of probable pocket at experimental sites |
| Bleeding upon probing | Baseline, one month, three month | presence or the absence of bleeding up to 30 second after probing with a William's periodontal probe |
| plaque index | Baseline,before PDT procedure, one month, three month | teeth number 16,12,24,36,32,44 are evaluated according to silness plaque index instruction were scored between 0 to 3 |
Countries
Iran
Outcome results
None listed