Sleep and Nocturnal Melatonin in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

The Effects of Methylphenidate on Sleep Patterns in Adults With ADHD: An Open Label Polysomnographic Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01329510

Acronym

ADHD

Enrollment

Registered

2011-04-06

Start date

2005-08-31

Completion date

2007-05-31

Last updated

2011-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Hyperactivity Disorder

Keywords

ADHD, Adult

Brief summary

This study will investigate the effects of methylphenidate on sleep in adults with Attention Deficit/ Hyperactivity Disorder (ADHD) using polysomnographic parameters.

Detailed description

Previous studies in children with Attention Deficit/ Hyperactivity Disorder (ADHD) have described the effect of stimulants on sleep patterns. However the data on adults with ADHD is sparse. The aim of this study is to investigate the effects of methylphenidate on sleep in adults with ADHD using polysomnographic parameters.

Interventions

DEVICEOne-night polysomnographic recordings

One-night polysomnographic recordings before and during methylphenidate treatment.

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* ADHD according to DSM-IV Criteria * Positive ASRS questionnaire

Exclusion criteria

* Brain damage * Brain encephalopathy * Borderline IQ * Affective disorder

Design outcomes

Primary

Measure	Time frame
polysomnographic parameters	one- night (day 1)

Secondary

Measure	Time frame	Description
sleep questionnaire	one week	mini sleep questionnaire

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026