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Events Before Death

International Comparison of Evolution of Clinical and Laboratory Parameters in Chronic Hemodialysis Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01329055
Enrollment
50000
Registered
2011-04-05
Start date
2000-01-31
Completion date
2010-05-31
Last updated
2011-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Renal Disease

Brief summary

Previous studies of the patients treated in RRI clinics suggest that hemodialysis patients undergo a certain consistent predictable pattern at the initiation of dialysis and before death. This pattern can be described as a group of patterns of patients' biological markers over a few months after starting dialysis and several months prior to death. Additional patterns can be observed that occur with changes in seasons or time of day. The aim of this study is to compare these patterns in patients treated in FMC-Asia, FMC-Europe, FMC-South America, and RRI-US populations. Noting that patterns in patient parameters are similar across continents, climates, and geographic variations only further accentuates the importance in the models that can predict patients' survival and provide an opportunity for timely intervention.

Interventions

None listed

Sponsors

Fresenius Medical Care North America
CollaboratorINDUSTRY
Maastricht University
CollaboratorOTHER
University of California
CollaboratorOTHER
Medical University Innsbruck
CollaboratorOTHER
Renal Research Institute
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 88 Years
Healthy volunteers
No

Inclusion criteria

* Hemodialysis vintage 2+ months

Design outcomes

Primary

MeasureTime frameDescription
Date of death10 years and 5 monthsThe main purpose of the study is developing an alert system that will help dialysis providers recognize patients who are at increased risk of death (or hospitalization). This alert system will be developed and can be utilized in patients treated all over the world.

Secondary

MeasureTime frame
HospitalizationsJanuary 2000 - May 2010

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026