A Study of Vitamin D in Subjects With Alopecia Areata

A Pilot Study of Vitamin D in Subjects With Alopecia Areata

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01328678

Enrollment

Registered

2011-04-05

Start date

2009-08-31

Completion date

2011-07-31

Last updated

2011-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia Areata

Keywords

Alopecia Areata, Vitamin D, Parathyroid, Calcium

Brief summary

The objective of this study is to assess the parathyroid-vitamin D-calcium axis in subjects with alopecia areata. The hypothesis behind this study is that hypovitaminosis D might contribute to the pathogenesis of alopecia areata.

Detailed description

Alopecia Areata (AA) is a T-Cell mediated, non-scarring, polygenic, autoimmune disease of the hair follicle. It has been reported to be associated with other autoimmune diseases, especially autoimmune thyroid disease and vitiligo. It is more common in females. Recently, vitamin D deficiency has been claimed to contribute to the pathogenesis of multiple autoimmune disease. There is a strong inverse correlation between the level of 25-hydroxyvitamin D levels and the autoimmune disease in adolescents.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Men and women who are at least 18 years old * Subjects with newly diagnosed with alopecia areata

Exclusion criteria

* Subjects who take supplemental Vitamin D, by itself or as a part of a multivitamin

Design outcomes

Primary

Measure	Time frame	Description
Vitamin D levels will be reported in subjects and correlated with the calcium and parathyroid levels.	Initial clinic visit (day 1)	This study consists of a single clinic visit. After subject has completed the informed consent process and meets eligibility criteria, a blood sample will be collected. Lab results from this one-time lab draw will be evaluated.

Countries

United States

Outcome results