Depression, HIV
Conditions
Keywords
HIV related adverse events, Immunological failure, virological failure, quality of life, depression, genotypic resistance
Brief summary
The purpose of this study is to study the HIV disease progression in HIV-infected Thai children.
Detailed description
This is a multicenter, observational cohort study. HIV-infected children from 5 institutions are followed to assess HIV disease progression: 1. Bamrasnaradura infectious disease institute,2. Faculty of Medicine Siriraj Hospital, Mahidol University, 3. Chiangrai Prachanukroh Hospital, 4. Sanpatong Hospital and 5. HIV-NAT, Thai Red Cross AIDS Research Center.
Interventions
DRUGstandard ART according to the Thai Ministry of Public Health national guidelines
Patients may receive any of the standard regimens. These regimens are recommended in the Thai Ministry of Public Health National guidelines for the treatment of HIV in children. Change of treatment will be according to the treating physicians.
Sponsors
Bamrasnaradura Infectious Diseases Institute
Mahidol University
Chiangrai Prachanukroh Hospital
Sanpatong Hospital
The HIV Netherlands Australia Thailand Research Collaboration
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
1. age \< 18 years old 2. Have confirmed HIV infection (ELISA,HIV-DNA PCR,HIV-RNA PCR) 3. Signed consent form
Exclusion criteria
1. Hospitalization 2. Emergency case 3. Incomplete Medical Record
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HIV related adverse events | 1 year | time to HIV related adverse events |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Immunological failure | 1 year | time to immunological failure |
| virological failure | 1 year | time to virological failure |
| quality of life | 1 year | time to change of quality of life |
| depression | 1 year | when patient develops depression |
| genotypic resistance | 1 year | time to genotypic resistance |
Countries
Thailand
Outcome results
None listed