Effects of Increased Muscle Mass on Resting Metabolic Rate

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01325038

Enrollment

Registered

2011-03-29

Start date

2008-01-31

Completion date

2009-08-31

Last updated

2011-03-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Subjects

Keywords

resting metabolic rate

Brief summary

Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and if this is affected by presumed increased caloric intake as compared with only proteins. Body-composition was measured with Dual-Energy X-ray Absorbimetry (DEXA) and RMR was measured by registration of CO2 production and O2 consumption.

Interventions

PROCEDUREIsometric exercise

Isometric exercise several times/week for three months

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy males

Exclusion criteria

* significant disease * inability to exercise

Design outcomes

Primary

Measure	Time frame	Description
change in resting metabolic rate	3 months	measurement of resting metabolic rate at baseline and at the end of the three month trial period

Secondary

Measure	Time frame	Description
change in muscle mass	3 months	measurement of muscle mass with DEXA at baseline and at the end of the three month trial period

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026