CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair

Multi-centre Observational Pilot-study for Evaluation of Variation in CA-125 and Other Inflammatory Markers in the Perioperative Period of Laparoscopic Ventral Hernia Repair

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01323361

Enrollment

Registered

2011-03-25

Start date

2011-04-30

Completion date

2012-08-31

Last updated

2013-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hernia

Keywords

inflammation, laparoscopy, hernia, incisional, trauma

Brief summary

The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair

Detailed description

CA-125 and other inflammatory markers as body temperature, CRP, PCT, leucocytes and neutrophils measured pre- and post-operatively - correlated to trauma size i.e. area of dissection, mesh size, number of fixation points etc.

Interventions

PROCEDURELaparoscopic ventral hernia repair

Patients operated with laparoscopic repair of ventral or incisional hernia

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults admitted for ventral or incisional hernia repair

Exclusion criteria

* Loss-of-domain * ASA above III * Liver failure * Abnormal CA-125 prior to surgery

Design outcomes

Primary

Measure	Time frame
Level of variation in inflammatory markers related to trauma impact	6 weeks post surgery

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026