Preopioid Versus Nonopioid in Total Knee Arthroplasty (TKA)

Acute Pain After Fast-track Total Knee Arthroplasty: Preoperative Opioid Versus Non-opioid

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01323179

Enrollment

140

Registered

2011-03-25

Start date

2011-03-31

Completion date

2013-02-28

Last updated

2013-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

Postoperative pain, Postoperative opioid requirements

Brief summary

Observational study evaluating pain response after total knee arthroplasty (TKA) in patients taking strong, weak or no opioids preoperatively.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients operated with elective, primary, unilateral total knee arthroplasty (TKA) (taking strong or weak opioid daily for minimum 4 weeks or opioid naive patients)

Exclusion criteria

* Bilateral / revision arthroplasty * Disease affection central or peripheral nerve function * Alcohol and medical abuse * Daily use of glucocorticoids * Malignancy * BMI \> 40 * Dementia or other cognitive dysfunction * Treatment of anxiety or depression

Design outcomes

Primary

Measure	Time frame	Description
Pain	24 hours	Pain during ambulation and at rest

Secondary

Measure	Time frame	Description
Pain	7 days	Pain during ambulation and at rest
Opioid consumption	7 days	—

Countries

Denmark

Outcome results