Anesthesia, General
Conditions
Keywords
extubation strategy
Brief summary
The primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via aspiration by evaluating and comparing the onset time of desaturation during spontaneous ventilation during awakening following general anesthesia.
Interventions
PROCEDUREPositive pressure extubation
Positive pressure extubation will be used for patients waking up from general anesthesia
PROCEDUREAspiration/suction extubation
Aspiration/suction extubation will be used for patients waking up from general anesthesia
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient is available for 1 hour of follow up * ASA 1 to 3 * The patient is schedules for orthopedic surgery (limbs) with general anesthesia
Exclusion criteria
* The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant * The patient is breastfeeding * Chronic respiratory insufficiency * Cardiopathy * Obstructive sleep apnea * Two or more predictive criteria for difficult mask ventilation (age \> 55 years, toothless, beard, snorer, BMI \> 26) * No predictive criteria for difficult intubation (SPIDS \<= 10)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spontaneous ventilation (air) time without desaturation after extubation (min) | 10 minutes | desaturation is defined as an SpO2\< 92% |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| presence/absence of a desaturation after extubation | 10 minutes | desaturation is defined as an SpO2\<92% |
| minimum Sp02 level after extubation (%) | 10 minutes | — |
| presence/absence of complications | 60 minutes | coughing, airway obstruction, laryngospasm, desaturation, apnea, vomiting in the first hour |
| presence / absence of therapeutic maneuvers | 60 minutes | includes oxygen therapy (or bezel ventimasque), Guedel airway, mask assistance, re-intubation during the first hour |
| presence/absence of any complication | 60 minutes | — |
Countries
France
Outcome results
None listed