Fluid Collections Management in Severe Acute Pancreatitis

Management of Sterile Fluid Collections in Patients With Severe Acute Pancreatitis:a Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01321060

Acronym

FCMSAP

Enrollment

Registered

2011-03-23

Start date

2011-01-31

Completion date

Unknown

Last updated

2012-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pancreatic Fluid Collection, Acute Pancreatitis

Keywords

severe acute pancreatitis, acute fluid collection, catheter drainage, repeated aspiration

Brief summary

Acute fluid collections is common in patients with severe acute pancreatitis (SAP). But the treatment for this is controversial. In this study, the investigators aim to evaluate the different effects of three different treatment protocols which is repeated aspiration, continuous catheter drainage and conservative treatment. The investigators suppose repeated aspiration could not only solve acute fluid collections, but also lower the rate of pancreatic infection.

Interventions

PROCEDUREAspiration

PROCEDURECatheter drainage

DRUGConservative treatment

Including antibiotics,somatostatin, proton pump inhibitors and sufficient fluid resuscitation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Symptoms and signs of acute pancreatitis according to Atlanta criteria and if pancreatic or/and peripancreatic fluid collections were confirmed by ultrasound and computed tomography examination * CT density \< 30Hu * Within 7 days from the onset of the disease * Available approach for percutaneous penetrate

Exclusion criteria

* Pregnant pancreatitis * Receiving surgery or aspiration before;need of early surgery * Infected fluid collection

Design outcomes

Primary

Measure	Time frame
pancreatic infection	28 days
mortality	28 days

Secondary

Measure	Time frame	Description
complications	28 days	intestinal fistula , major bleeding, etc.
ICU duration	day one until discharge	—
inflammation parameters	28 days	—
SIRS	28 days	—
MODS	28 days	—
hospital duration	day one until discharge	—
intra abdominal pressure	28 days	—

Countries

China

Contacts

Primary ContactWeiqin Li, Dr

kkb9832@gmail.com+86-025-80860066

Backup ContactZhihui Tong, Dr

njzyantol@hotmail.com+86-025-80860066

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026