Improved Analysis Methods for Infusion Tests

Novel Infusion Method for Describing CSF Dynamics

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01319136

Enrollment

Registered

2011-03-21

Start date

2009-03-31

Completion date

2010-08-31

Last updated

2011-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Normal Pressure Hydrocephalus

Keywords

new infusion test method, reference method, cerebrospinal fluid dynamics

Brief summary

Objective: Patients with Idiopathic Normal Pressure Hydrocephalus are improved with shunt surgery. To increase the accuracy of the diagnosis, supplementary tests that characterize the cerebrospinal fluid (CSF) dynamics are used. The infusion test is one of these, used for shunt surgery selection and postoperative evaluation of shunt function. Forty-eight patients that had a preoperative investigation because of communicating hydrocephalus at the university hospitals in Umeå and Uppsala, Sweden, participated in the study. The purpose of this study was to evaluate a new method, with a new infusion protocol and new analysis methods, and compare it to the current method.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* preoperative investigation because of communicating hydrocephalus * ventriculomegaly (Evans ratio \> 0.3) * no obstruction to CSF flow at visual inspection

Exclusion criteria

* postoperative infusion test investigations * patients that were unable to understand instructions

Countries

Sweden

Outcome results