Obesity
Conditions
Keywords
Obesity prevention, appetite regulation, hyperlipidemia
Brief summary
The aim is to study the effect of milk versus cheese on fecal fat excretion and blood lipids. To do this, a randomized crossover intervention study with 3 14-day periods (control diet, milk diet, cheese diet) will be conducted in 16 young males. Fasting blood samples will be collected before and after each period, and fecal samples will be collected for the last 5 days in each period.
Interventions
OTHERDietary intervention (without dairy products)
Control diet without dairy products
OTHERDietary intervention (high milk content)
Diet with a high content of milk (\ 1200 mg Ca/d from milk)
OTHERDietary intervention (high cheese content)
Diet with a high content of cheese (\ 1200 mg Ca/d from cheese)
Sponsors
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy males * BMI 20-28 mg/m2
Exclusion criteria
* Smoking * Medicine use * Dietary supplements * Lactose intolerance, milk allergy * Dislike of dairy products * Excessive physical activity (\> 10h/wk) * Known chronic illnesses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fecal fat excretion | During day 10-14 in each period | Total excretion of fecal fat (grams/day)avaraged over five days |
Secondary
| Measure | Time frame |
|---|---|
| Total, HDL and LDL cholesterol | Day 1 and 14 in each period |
| Triglycerides | Day 1 and 14 in each period |
| Appetite sensation | Assessed on day 1, 8 and 14 in each period |
Countries
Denmark
Outcome results
None listed