Healthy
Conditions
Keywords
cone outer segment tips line, Optical coherence tomography
Brief summary
The aim of this study is to investigate the incidence and possible causes of obscured or disrupted cone outer segment tips line at fovea in spectral-domain optical coherence tomography images of normal eyes.
Detailed description
Thirty-seven eyes of 37 individuals without eye diseases were included in this study. Optical Coherence Tomography (OCT) images were taken using Cirrus HD-OCT (Carl Zeiss Meditec) with 5 line raster and high-definition 5 line raster modes. Images with signal strength weaker than 5/10 were excluded. Distinction of COST line and the integrity of COST line, external limiting membrane, and the photoreceptor inner segment and outer segment junction at the fovea were recorded. Demographic data, refractive error of the eyes, signal strengths of the OCT images were acquired for analysis.
Interventions
OTHEROptical coherence tomography
Optical coherence tomography
Sponsors
Kyorin University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* individuals without eye diseases
Exclusion criteria
* individuals with eye diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Microstructural analysis by Spectral domain optical coherence tomography | one year | SD-OCT images of 6 mm scans were taken using Cirrus HD-OCT (OCT 4000, Carl Zeiss Meditec, Dublin, CA) with 5 line raster (5LR) and high-definition 5 line raster (HD5LR) modes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity | one year | Each subject had a routine eye examination including measuring best-corrected visual acuity (BCVA) and intraocular pressure. |
Countries
Japan
Outcome results
None listed