Knee Osteoarthritis
Conditions
Keywords
Knee, Osteoarthritis, Effusion.
Brief summary
The present study investigated whether the presence of fluid in the joint affected peak torque and the root mean square (RMS) values of surface electromyography (EMG) in patients symptomatic for osteoarthritis (OA).
Detailed description
Several studies have shown that knee effusion influenced quadriceps muscle activity and induced quadriceps arthrogenic muscle inhibition in normal volunteers. However, the effect of joint effusion on the quadriceps of patients with OA is controversial,and few patients with OA have been included in studies of joint effusion.
Interventions
OTHERnormal saline injection
20 cc normal saline injection into knee joint
OTHERsham injection
no saline injection
Sponsors
The Catholic University of Korea
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
50 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 50 years old or older with knee osteoarthritis * knee pain without joint effusion confirmed by ultrasonography
Exclusion criteria
* the presence of knee joint effusion determined using US * a history of knee injury or surgery * a history of knee injection within 3 months * a history of inflammatory arthritis * taking anticoagulants * balance or gait disturbance * diabetes mellitus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the peak torque of the knee extensors | within 5 minutes after intervention | to evaluate the effect of effusion on the peak torque of the knee extensors |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the root mean square values of the vastus medialis and vastus lateralis muscles | within 5 minutes after intervention | to evaluate the effect of effusion on the RMS of the vastus medialis (VM) and vastus lateralis (VL) muscles |
Countries
South Korea
Outcome results
None listed