Heart Diseases
Conditions
Brief summary
The purpose of this study is to determine whether postoperative nutritional support improves postoperative outcomes in cardiac patients with malnutrition .
Interventions
DIETARY_SUPPLEMENTEnsure, Abbott Nutrition
Enteral feeding Ensure, Abbott Nutrition 400 ml per day for seven postoperative days
standard hospital diet
Sponsors
Meshalkin Research Institute of Pathology of Circulation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Absolute lymphocyte count \< 1500 * Albumin \<35 g/L * Body mass index\<21 kg/m2 * B class of nutritional status according to Subjective Global Assessment
Exclusion criteria
* Hepatitis B, C * Total circulatory arrest * Absence of informed consent signed * Chronic liver diseases * Gastric resection in patient's history * Physical limitations of normal feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality | 1 month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total lymphocyte count | before operation, 7, 14, 21 postoperative days | — |
| Serum albumin | Before operation, 7, 14, 21 postoperaitve days | — |
| Serum prealbumin | Before operation, 7, 14, 21 postoperaitve days | — |
| Retinol-binding protein | Before operation, 7, 14, 21 postoperaitve days | — |
| Postoperative complications | 1 month | Cardiac arrhythmia, infectious complications. |
Countries
Russia
Outcome results
None listed