Effect of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery

Effect of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery: Implication of Preoperative Cyanosis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01311310

Enrollment

Registered

2011-03-09

Start date

2009-10-31

Completion date

2011-12-31

Last updated

2012-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cyanosis

Keywords

troponin, open heart surgery, children

Brief summary

This study is conducted in order to evaluate the effect of remote ischemic preconditioning on children undergoing cardiac surgery, especially focusing on possible differences according to preoperative cyanosis.

Interventions

OTHERRIPC (remote ischemic preconditioning)

RIPC will be performed by four 5-min cycles of lower limb ischemia and 5 in reperfusion using blood-pressure cuff inflated to a pressure 15 mmHg greater than the systolic arterial pressure measured via arterial line.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

1 Months to 10 Years

Healthy volunteers

Inclusion criteria

* open heart surgery under cardiopulmonary bypass: ventricular septal defect, tetralogy of Fallot

Exclusion criteria

* chromosomal defect * airway and parenchymal lung disease blood disorder * isolated atrail septal defect * immunodeficiency

Design outcomes

Primary

Measure	Time frame	Description
troponin level	within the 1 day after operation	troponin level will be checked 1, 6, 12 and 24 hours after operation. Ater making a graph (troponin-time), area under the curve will bw calculated.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026