The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01310920

Enrollment

400

Registered

2011-03-09

Start date

2011-02-28

Completion date

Unknown

Last updated

2011-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sick Sinus Syndrome

Brief summary

Evidence has been documented for the close relationship between the arrhythmia pathogenesis and the gene expression in renin-angiotensin system. However, it remains unclear for involvement of RAS in the pathogenesis of non-familial sick sinus syndrome. The researchers thus investigated the possible relationship between non-familial sick sinus syndrome and the polymorphism and haplotype of the AGT promoter.

Interventions

OTHERobservation

genotyping

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* sick sinus syndrome

Exclusion criteria

* 1.Severe systemic disease. * 2.Acute coronary syndrome. * 3.bradycardia with reversible cause.

Countries

Taiwan

Contacts

Primary ContactJan-Yow Chen, MD

janyow@ms77.hinet.net+886-4-22062121

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026