Streptococcal Sore Throat
Conditions
Keywords
Pharyngitis, Group A β-hemolytic Streptococci, Exudate, Erythema Penicillin, Amoxicillin
Brief summary
In some studies once daily amoxicillin therapy might be treatment of choice for Group A β-hemolytic Streptococcus pharyngitis in comparison with three to four times daily treatment with oral penicillin V.
Interventions
DRUGAmoxicillin
DRUGIntramuscular Benzathin Penicillin G
It is mentioned underlined in page 10 in research. (Once the throat swab was taken and cultured on plate at the place where the child was examined, hygiene teacher was trained about how to prepare the oral amoxicillin suspension and how to give it to the child. 750 milligrams of amoxicillin was thereafter given to the patient and in order not to infect other school children, the patient was sent home. The following morning, the patient would come to school and was given the second dose of amoxicillin by the hygiene teacher. All oral drugs were bought from a creditable company. In the injection group, 600000 units of penicillin was administered to children who weigh less than 27 kilograms and 1200000 units of penicillin was administered to children who weigh more. After 48 hours, patients were examined again when the result of first culture was ready)
Sponsors
Azad University of Medical Sciences
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
6 Years to 15 Years
Inclusion criteria
Inclusion Criteria: 1. Age of 6 to 15 years old. 2. The criteria in clinical examination including objective signs (fever, Erythema or exudate of tonsils, enlarged lymph nodes) and subjective sign(sore throat). Neck tenderness, abdominal pain and pharynx petechia were also considered. 3. No antibiotic was used during the week before. 4. -Performing throat culture before the initiation of drug administration 5. Positive throat culture indication GABHS 6. No previous history of allergy to penicillin .
Exclusion criteria
1. Age of below 6 years old or above 15 years old. 2. No signs of pharyngitis in the clinical examination 3. Antibiotic use during the week before. 4. Throat culture was not performed before the initiation of drug administration. 5. Negative throat culture or the culture indicates a microorganism other than GABHS. 6. History of allergy to penicillin 7. Not using drugs or not following the treatment in the field of having the second culture performed.
Countries
Iran
Outcome results
None listed