Prematurity of Fetus
Conditions
Keywords
mydriatic, NIRS, preterm, eye drops, cerebral, mesenteric oxygenation
Brief summary
Near infrared spectroscopy offers the possibility of noninvasive and continuous bedside investigation of cerebral and mesenteric oxygenation in newborn infants. Using this technique the investigators investigated the effect of mydriatic eye drops on cerebral and mesenteric oxygenation in preterm infants
Detailed description
The cerebral and mesenteric oxygenation will be measured by NIRS before, during and after the mydriatic eye drops are instilled.
Interventions
NIRS device used in this study, the optical field includes a volume of tissue approximately 2 cm deep to the surface probe with a 4-mm source-detector distance, and thus, organ-specific monitoring is feasible in small patients. With informed consent, the investigators applied NIRS probes to the forehead and abdomen for cerebral (rSO2C) and abdominal (rSO2P) regional oxygen saturation measurements.
Sponsors
Zekai Tahir Burak Women's Health Research and Education Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
28 Days to 90 Days
Healthy volunteers
No
Inclusion criteria
1. \< 32 gestational age and/or \< 1500gr. 2. ≥ 28th day preterm infants 3. Instilled mydriatic eye drops for ROP examination
Exclusion criteria
1. Sepsis 2. Shock 3. Severe intracranial hemorrhage 4. NEC 5. Abdominal and cranial surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Effect of Mydriatic Eye Drops on Cerebral and mesenteric Oxygenation | one year | By NIRS cerebral and mesenteric oxygenation will be measured before, during and after mydriatic eye drops are instilled. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactHatice Tatar Aksoy, MD
Backup ContactUgur Dilmen, Prof.
Outcome results
None listed