Pain, Postoperative
Conditions
Brief summary
Using Magnetic resonance (MR) scanning and ultrasonography the investigators wish to investigate, in what way a known volume of local anesthetic injectate will be distributed in the transverse abdominis plane (TAP) in young healthy male volunteers. The investigators compare the anatomical distribution of the local anesthetic injectate in the TAP when performing an ultrasound-guided classical TAP block and a Dual TAP block. The investigators also want to compare the spread of anesthetized frontal dermatomes when performing an ultrasound-guided classical TAP block and a Dual TAP block.
Detailed description
There has been much debate as to what extent the classical TAP block will anesthetize more than the frontal dermatomes (TH10-Th12/L1). Some cadaver studies have been performed with injection of dye in the classical TAP. However, it is still not clear whether a single injection of local anesthetic in the classical TAP block position will reach the more cephalad and medial intercostal TAP plexus (Th6-Th9). In this study the investigators use MR scanning and ultrasonography to investigate in what way a known volume of local anesthetic injectate will be distributed in the transverse abdominis plane (TAP) in young healthy male volunteers. The investigators compare the anatomical distribution of the local anesthetic injectate in the TAP when performing an ultrasound-guided classical TAP block and a Dual TAP block. The investigators also want to compare the spread of anesthetized frontal dermatomes when performing an ultrasound-guided classical TAP block and a Dual TAP block.
Interventions
DRUGBupivacaine
On both sides of the abdomen 30 ml of bupivacaine 2.5 mg/ml will be injected. This is a total of 60 ml of bupivacaine 2.5 mg/ml.
PROCEDUREInjection
Injection under ultrasound-guidance
Sponsors
Bispebjerg Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* healthy male * 18 years old or more * had no previous abdominal surgery * no regular medication * no coagulation disorders * no claustrophobia
Exclusion criteria
* if the volunteer is not able to accept an uncomplicated administration of a classical (single) or dual TAP block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distribution of local anesthetic evaluated by MR scanning | 30 minutes after administering the TAP blocks |
Secondary
| Measure | Time frame |
|---|---|
| Spread of anesthetized frontal dermatomes | 30 minutes after administering the TAP blocks |
Countries
Denmark
Outcome results
None listed