Pulsed Dye Laser for the Psoriatic Nail

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01303185

Enrollment

Registered

2011-02-24

Start date

2011-01-31

Completion date

2012-02-29

Last updated

2014-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriatic Nail

Keywords

Psoriatic Nail, Pulsed dye laser

Brief summary

The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Detailed description

Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

* Psoriatic nail refractory to other topical and systemic treatment therapy * ≧ 16 years old

Exclusion criteria

* Patient with pregnancy * Patient with photo sensitivity * Patient with severe wound around finger nails or paronychia * Patient with hypersensitivity to Tazarotene cream

Design outcomes

Primary

Measure	Time frame
NAPSI	3rd and 6th months
global physician assessment	3rd and 6th months

Countries

Taiwan

Outcome results