Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief?

Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief After Total Knee Arthroplasty or Should an Addition of Sciatic, Obturator and Lateral Femoral Cutaneous Nerve Blocks be Recommended?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01303120

Enrollment

107

Registered

2011-02-24

Start date

2011-05-31

Completion date

2013-12-31

Last updated

2015-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Pain

Brief summary

The aim of this study is to compare the efficacy of the analgesic effect of the preoperative femoral nerve block alone versus combined femoral, sciatic, obturator and lateral femoral cutaneous nerve blocks in patients after TKA in the immediate postoperative period.

Detailed description

Bupivacaine will be used for all the nerve blocks.

Interventions

DRUGFemoral Nerve Block

Preoperative Bupivacaine 0.5%, perineurally as single shot

DRUGCombined nerve blocks

Preoperative Bupivacaine 0.5%, perineurally as single shot

DRUGPatient-controlled analgesia

Patient controlled analgesia with morphine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

30 Years to 85 Years

Healthy volunteers

Inclusion criteria

* ASA I-III * Undergoing two TKA * Understanding PCA protocol

Exclusion criteria

* Skin infection near injection site * Allergy to local analgesics * Peripheral neuropathy * Coagulopathy * Dementia * Proven opioid dependency

Design outcomes

Primary

Measure	Time frame
Efficacy of single short femoral nerve block	Three days

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026