The Effects of Normobaric Hypoxia on Blood Glucose Levels.

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01302782

Enrollment

Registered

2011-02-24

Start date

2012-12-31

Completion date

2013-08-31

Last updated

2013-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucose

Keywords

Altitude, Glucose

Brief summary

The purpose of this research study is to observe whether there is a change in blood glucose levels in response to a 2 hour oral glucose tolerance tests (OGTT) during acute normobaric hypoxia (short term low oxygen levels at normal ambient air pressure).

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

(non-diabetics): * Tricare Insurance Beneficiary (military insurance) receiving care at Nellis AFB * 5 males with a BMI \< 25; 5 males with a BMI \> 25 at least 18 years of age (MOFH personnel and DoD beneficiaries). * 5 females with a BMI \< 25; 5 females with a BMI \> 25 at least 18 years of age (MOFH personnel and DoD beneficiaries).

Exclusion criteria

(non-diabetics): * History of abnormal fasting glucose. * Pulmonary disease. * Any medications that change glucose control to include systemic steroid and diabetic medications. * History of claustrophobia. * Pregnant or breast feeding. * Non-English speaking. * Physical inability to wear/use the ROBD2 Inclusion Criteria (diabetics): -5 males and/or females, at least 18 years of age, that are type 2 diabetics (MOFH personnel and DoD beneficiaries).

Design outcomes

Primary

Measure	Time frame	Description
Change in glucose levels at altitude	1 year	Subjects will be placed on a Reduced Oxygen Breathing Device (ROBD2) to simulate 3 different altitudes at three separate and distinct time periods (ground, 8,000 feet and 12,000 feet) then obtain c-peptide and 2-hour OGTT to determine blood glucose changes during acute normobaric hypoxia.

Outcome results