Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction

Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction Due to Spinal Cord Injury

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01299792

Enrollment

Registered

2011-02-18

Start date

2009-08-31

Completion date

2011-10-31

Last updated

2024-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Injury

Keywords

spinal cord injury, urodynamics, ultrasound, neurogenic bladder dysfunction

Brief summary

Video-urodynamic investigations are regarded as the current standard diagnostics for neurogenic bladder dysfunction in patients with spinal cord injury. This examination is exact, but time consuming, costly and associated with the risk of urinary tract infection. In patients with lower urinary tract symptoms due to benign prostate hyperplasia, sonographic measurement of bladder wall thickness has been demonstrated to be able to replace urodynamic testing for the diagnosis of infravesical obstruction. Hypothesis: measurement of bladder wall thickness in patients with neurogenic bladder dysfunction due to spinal cord injury is closely related to the known risk factors for upper urinary tract deterioration (bladder compliance, detrusor leak point pressure) in this group of patients and can therefore replace urodynamic examination in selected cases.

Interventions

OTHERsonographic measurement of bladder wall thickness

measurement of bladder wall thickness by ultrasound at different filling states of the bladder during urodynamic investigation

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* neurogenic bladder dysfunction due to spinal cord injury * ability to understand German language * willingness and capability to undergo urodynamic testing * age \> or = 18 years

Exclusion criteria

* acute urinary infection at the time of examination * known bladder tumor or bladder stone * age \< 18 years * not capable to understand aim and purpose of the examination

Design outcomes

Primary

Measure	Time frame	Description
correlation bladder wall thickness and detrusor compliance	calculated from maximum bladder filling	measurement of detrusor compliance at maximum bladder volume; measurement of bladder wall thickness at maximum bladder volume

Secondary

Measure	Time frame	Description
correlation bladder wall thickness and maximum detrusor pressure	measurement at maximum bladder capacity	correlation between bladder wall thickness and maximum detrusor pressure during the urodynamic storage phase

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026