Stroke
Conditions
Brief summary
The purpose of this study is to compare the improvement in ankle control and brain activation in subjects with stroke resulting from two different forms of telerehabilitation: tracking training, emphasizing accurate movements, versus movement training, involving simple movements. Hypotheses: 1. The Track group will show greater improvement in ankle range of motion compared to the Move group. 2. The Track group will show greater improvement in ankle tracking accuracy and greater changes in fMRI (increase in relative volume of activation for ipsilesional sensorimotor cortex, increase in laterality index, and decrease in blood-oxygen-level-dependent (BOLD) signal intensity index) compared to Move group. 3. The Track group will show greater improvement in tracking accuracy at an untrained joint (knee) compared to the Move group. 4. The Track group will show greater improvement in standing balance. 5. The Track group will show greater improvement in walking speed and ankle dorsiflexion during gait compared to the Move group.
Interventions
BEHAVIORALankle tracking training
one group will use the ankle for tracking, the other group will use the ankle for simple movement
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Single stroke with an ischemic infarct. 2. Between 18 and 85 years of age. 3. Time since stroke onset must be \>6 months. 4. Cannot be receiving any rehabilitation therapy. 5. Impaired ankle dorsiflexion/plantarflexion but at least 10 degrees of active motion. 6. Cognition level must be at least 24 out of 30 on the Mini-Mental Examination 7. Able to ambulate at least 100 feet independently. training.
Exclusion criteria
1. Cannot have any neuromuscular disorder other than stroke that impairs ankle motion. 2. Cannot have an executive function score on Stroop Interference Test of \<37. 3. Cannot have a score on the Beck Depression Inventory of \>10. 4. Cannot have ataxia, apraxia, receptive aphasia, hemi-neglect, or severe visual field cut . 5. Cannot be pregnant nor have indwelling metal or medical devices incompatible with fMRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ankle range of motion | Measurement at pretest, posttest and followup |
Countries
United States
Outcome results
None listed