Spinal Cord Injury, Vesico-ureteral Reflux
Conditions
Keywords
vesico-ureteral reflux, neurogenic bladder dysfunction, spinal cord injury
Brief summary
The purpose of this study is to investigate the incidence of reflux in patients with spinal cord injury in relation to the lesion level, duration of injury and bladder management
Detailed description
Vesico-ureteral reflux was the main cause for renal failure and reduced life expectancy in patients with neurogenic bladder dysfunction due to spinal cord injury. Neurogenic detrusor overactivity leads to high intravesical pressure and may induce reflux. Decreasing intravesical pressure and increasing bladder capacity is necessary to prevent reflux and secondary renal failure.
Interventions
PROCEDUREvideo-urodynamic examination
Assessment of bladder function during video urodynamic determine of incidence degree and localization of vesico ureteral reflux based on the result of video urodynamics
Sponsors
Balgrist University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Spinal cord injury * Neurogenic lower urinary tract dysfunction * Written informed consent
Exclusion criteria
* Lower urinary tract dysfunction due to other causes than spinal cord injury
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence and degree of vesico ureter renal reflux | average: yearly scheduled control | video urodynamic, ultrasound examination |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Medication | average: yearly scheduled examination | name of drugs and applied dosis |
| possible complications | average: yearly scheduled examination | urinary tract infection, pyelonephritis, renal dysfunction |
| pdet (cmH2O) | average: yearly scheduled control | urodynamic parameter, detrusor pressure |
| compliance mL/cmH2O | average: yearly scheduled control | Compliance is the change in volume divided by change in detrusor pressure expressed as mL/cmH2O. |
| bladder management | average: yearly scheduled control | most common: intermittent catheterisation, indwelling catheter, external condom urinal for male patients |
| maximum cystometric capacity | average: yearly scheduled control | the volume at which a patient, with normal sensation, fells he/she can no longer delay micturition |
Countries
Switzerland
Outcome results
None listed