Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01296230

Enrollment

Registered

2011-02-15

Start date

2011-02-28

Completion date

2017-02-28

Last updated

2013-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Semen Quality, Varicocele

Brief summary

The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.

Interventions

PROCEDUREHormone and semen measurements before varicocelectomy

Before surgery we will measure sex-hormone levels and semen parameters. This will be repeated after the varicocelectomy to record any changes.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Varicocele (grade 1-3) and surgery planned for this condition * At least 18 years of age

Exclusion criteria

* Fever within 3 months before the first semen sample * Malformations of the uro-genital tract * Karyotype other than 46, XY or Y micro deletions * Endocrine disease * Chronic disease * Medications which reduce semen quality * Epididymitis within 6 months before surgery

Design outcomes

Primary

Measure	Time frame
Change in semen parameters	February 2017 (anticipated duration of the study)

Secondary

Measure	Time frame
Change in hormone levels	February 2017 (anticipated end of the study)

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026