Papillomavirus Infections
Conditions
Keywords
HPV, Cervical Cancer
Brief summary
The purpose of this study is to determine rates of oral and genital human papillomavirus (HPV) infections, and look at risk factors for HPV infection in healthy mid-adult women.
Detailed description
The investigators propose a longitudinal study of 500 women in order to determine rates and risk factors for HPV infections in 30-50 year old women. Participants will be followed for 6 months and will be asked to complete online questionnaires on their health, sexual behavior, HPV vaccinations, and cervical cancer screening. The investigators will ask participants to self-collect monthly vaginal swab samples and self-collect 2 oral swab samples. Women will also be asked to provide 2 blood samples. All swab samples will be tested for type-specific HPV deoxyribonucleic acid (DNA) using a polymerase chain reaction (PCR)-based assay, blood samples will be tested for HPV antibodies.
Interventions
None listed
Sponsors
University of Washington
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* affiliated with the University of Washington (student, staff, faculty) * willing to self-collect vaginal samples at home for HPV testing * able to provide informed consent
Exclusion criteria
* pregnant * have had hysterectomy * serious medical condition which prevents completion of activities of daily living
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of type-specific HPV DNA in self-collected oral and vaginal swab samples | once a month for 6 months |
Countries
United States
Outcome results
None listed