Topic Insulin Accelerates Wound Healing in Diabetes

Topic Insulin Accelerates Wound in Diabetes

Status

Completed

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01295177

Acronym

insulin

Enrollment

Registered

2011-02-14

Start date

2004-01-31

Completion date

2007-09-30

Last updated

2011-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus, Wounds

Keywords

wound healing, diabetes mellitus

Brief summary

The purpose of this study is to determine whether topic insulin is effective to accelerates wound healing in diabetes patients

Detailed description

Wound healing is impaired in diabetes mellitus, but the mechanisms involved are not well established. The purpose of this study was to investigate the effect of a topic insulin cream on wound healing in diabetic patients. age eligible for study:18 years old-older gender eligible for study:both accepts healthy volunteers:no have a proband with T1DM or T2DM. A proband is an individual with more than one year of diagnosis. have proband with a wound that is difficult to be healed for at least three months. patients with serum creatinine \<1.5mg/dl Does not satisfy the above inclusion criteria infection diagnosed wound patients with cellulitis, venous stasis, inadequate perfusion, osteomyelitis and patient's inability to attend clinics for follow up

Interventions

DRUGtopic cream insulin

Intervention: Placebo cream versus insulin cream. Patients with wounds for more than 3 months without infection. These patients were treated with placebo cream or insulin cream. The placebo or insulin were used for 8 weeks.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

age eligible for study:18 years old-older gender eligible for study:both accepts healthy volunteers:no have a proband with T1DM or T2DM. A proband is an individual with more than one year of diagnosis. have proband with a wound that is difficult to be healed for at least three months. patients with serum creatinine \<1.5mg/dl

Exclusion criteria

Does not satisfy the above inclusion criteria infection diagnosed wound patients with cellulitis, venous stasis, inadequate perfusion, osteomyelitis and patient's inability to attend clinics for follow up

Design outcomes

Primary

Measure	Time frame
% of Wound healing closing measured each week	7 days

Secondary

Measure	Time frame
Complete wound healing	8 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026