Effect of Short-term Chinese Tea-flavor Liquor Consumption

Phase 1 Study of Chinese Tea-flavor Liquor

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01294995

Acronym

ESTCTFLC

Enrollment

Registered

2011-02-14

Start date

2010-10-31

Completion date

2010-11-30

Last updated

2011-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases

Keywords

short term consumption, Chinese liquor, serum lipids, uric acid, inflammation biomarkers

Brief summary

Human studies of Chinese liquor are sparse. The investigators hypothesize that short-term Chinese Tea-flavor liquor (TFL) consumption may be beneficial to inflammation biomarkers and CVD risk factors. Guizhou Meijiao Liquor (GML) is a traditional Chinese liquor, fermented from sorghum, corn, sticky rice, wheat and rice, while TFL is a novel Chinese liquor fermented from above 5 grains plus green tea. Forty-five volunteers(23 males, 22 females) were selected to participate a paralleled randomized trial drinking 30 mL two kinds of Chinese liquors: TFL and GML respectively with meal every day for 28 days. Serums of volunteers were collected for analyzing serum lipids, inflammation biomarkers and CVD risk factors. TFL could significantly decrease systolic blood pressure of males, but increase diastolic blood pressure of females. TFL could also decreased blood lipid of volunteers, especially for females. Both liquor significantly decrease serum uric acid and glucose in males and females. The effect of the two liquors on inflammation biomarkers were complicated and needs further research work. TFL may possess more beneficial effect on CVD risk factors than GML probably because of the special fermentation products of green tea with other grains.

Interventions

DIETARY_SUPPLEMENTTea-flavor Liquor

30 mL of Tea-flavor Liquor(45% alcohol content)

DIETARY_SUPPLEMENTGuizhou Meijiao Liquor

30 mL of Guizhou Meijiao Liquor (45% alcohol content)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

23 Years to 28 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy male and female volunteers

Exclusion criteria

* Subjects with a history of liver disease, diabetes, or heart disease * Smokers

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026