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Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture

Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01294930
Acronym
IOPC
Enrollment
45
Registered
2011-02-14
Start date
2011-01-31
Completion date
2012-07-31
Last updated
2013-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fracture

Keywords

hip fracture, mortality, complications

Brief summary

Patients operated for hip fractures are older and have several conditions that have negative influences on the perioperative and postoperative prognosis. Hip fractures can also be painful, which is stressful for the physiology of the patient. Many old patients have received to little fluid intake. They often have diuretic therapy, which even worsens dehydration/hypovolemia. Some patients have to wait several days for surgery. Several studies have shown a high degree of complications and an increased mortality in this patient group. Early preoperative optimization can improve the outcome. The available methods for optimization of the patient are complicated and time consuming. The investigators wish with this study to try new approaches to find which patients still are dehydrated when they come to the operation ward. The aim is to measure the color and density of the urine as well as to register the the variability in the plethysmographic curve before spinal anaesthesia. These results will be compared to circulatory instability during and after surgery as well as to postoperative complications.

Detailed description

All patients with hip fractures planed fore surgery at the Hospital in Norrkoping will come into consideration to participate in study. Many will however not be able to give consent. These will not be included in the study. Directly preoperatively urine will be collected. Color and density will be measured/registered. The pulseoximeter reading will be registered (Saturation, pulse, PI and PVI) before spinal anaesthesia and after spinal anaesthesia as well as during the surgery. Two to three days postoperatively a follow up will be performed, to register complications (Circulatory instability, confusion, infection, affected kidney function/creatinine rise). 30 day postoperative mortality will also be controlled. These results will be compared, to see if pulse oximeter readings or urine concentration can predict complications.

Interventions

OTHERUrine density

measurement of urine color, density and plethysmographic variability index before and during surgery.

Sponsors

Vrinnevi Hospital
CollaboratorOTHER
University Hospital, Linkoeping
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients with hip fracture * operation for the hip fracture * informed consent

Exclusion criteria

* patients not giving consent * patients not being able to understand information

Design outcomes

Primary

MeasureTime frameDescription
mortality30 days30-day mortality related to indices of dehydration (urine and pulse oximetry)

Secondary

MeasureTime frameDescription
operative and postoperative complications3 daysNumber of complications according to a prospective list

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026